| The role of HSAL (SALL) genes in proliferation and differentiation in normal hematopoiesis and leukemogenesis. | |
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MedLine Citation:
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PMID: 22074632 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The National Blood Foundation (NBF) support was critical in the author's research career development. The NBF support came in the form of a start-up seed grant that she got from the American Association of Blood Banks, an organization that advances the practice and standards of transfusion medicine and cellular therapies and an organization in which she is a proud member. The NBF grant enabled her to keep up with her transfusion medicine practice while pursuing her passion to be a physician scientist. During its funding period, she was able to obtain critical preliminary bench data and to secure several National Institutes of Health grants with over a million dollars direct cost. In addition, the knowledge gained from the NBF-supported projects is currently being translated into medical practice in her lab by testing on cord blood expansion. She is looking forward to spending the upcoming years of her professional career bridging bedside observations on transfusion medicine with bench experiences and then utilizing that bench-derived knowledge in the practice of transfusion medicine. |
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Authors:
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Li Chai |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Transfusion Volume: 51 Suppl 4 ISSN: 1537-2995 ISO Abbreviation: Transfusion Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-14 Completed Date: 2012-01-05 Revised Date: 2012-01-16 |
Medline Journal Info:
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Nlm Unique ID: 0417360 Medline TA: Transfusion Country: United States |
Other Details:
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Languages: eng Pagination: 87S-93S Citation Subset: IM |
Copyright Information:
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© 2011 American Association of Blood Banks. |
Affiliation:
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Department of Pathology, Joint Program in Transfusion Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. lchai@partners.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Division Cell Transformation, Neoplastic / genetics* DNA-Binding Proteins / genetics, physiology Embryonic Development / genetics Female Genes, p53 Hematopoiesis / genetics*, physiology Homeodomain Proteins / genetics*, physiology Humans Intracellular Signaling Peptides and Proteins / genetics, physiology Leukemia, Myeloid, Acute / genetics* Lymphoma / genetics* Mice Mice, Knockout Ovarian Neoplasms / genetics Transcription Factors / deficiency, genetics*, physiology Zinc Fingers / genetics*, physiology |
| Grant Support | |
ID/Acronym/Agency:
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P01DK080665/DK/NIDDK NIH HHS; P01HL095489/HL/NHLBI NIH HHS; R01HL092437/HL/NHLBI NIH HHS; R01HL092437-A1S1/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/DNA-Binding Proteins; 0/Homeodomain Proteins; 0/Intracellular Signaling Peptides and Proteins; 0/SALL1 protein, human; 0/SALL2 protein, human; 0/SALL3 protein, human; 0/SALL4 protein, human; 0/Sall1 protein, mouse; 0/Sall2 protein, mouse; 0/Sall3 protein, mouse; 0/Sall4 protein, mouse; 0/Transcription Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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