| The role of FDG-PET/CT imaging in head and neck malignant conditions: impact on diagnostic accuracy and patient care. | |
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MedLine Citation:
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PMID: 17599580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To assess the value of positron emission tomography/computed tomography (PET/CT) with 18F-Fluorodeoxyglucose (FDG) in patients with head and neck carcinoma as compared with PET and conventional imaging alone, and to assess the impact of PET/CT on further clinical management. STUDY DESIGN: Prospective nonrandomized study. SETTING: Ninety patients with head and neck tumors had 107 PET/CT examinations. RESULTS: The study analysis showed that PET/CT had a sensitivity of 89%, specificity 95%, PPV 94%, NPV 90%, and accuracy of 92%. PET/CT altered management in 51 patients (56%). PET/CT eliminated the need for previously planned diagnostic procedures in 24 patients, induced a change in the planned therapeutic approach in 21 patients and guided biopsy in 6 patients. CONCLUSIONS: PET/CT is an imaging modality with high diagnostic performance in the assessment of head and neck cancer, and induced a change in further clinical management in more than half of the study population. |
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Authors:
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Arie Gordin; Avishay Golz; Zohar Keidar; Marcello Daitzchman; Rachel Bar-Shalom; Ora Israel |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery Volume: 137 ISSN: 0194-5998 ISO Abbreviation: Otolaryngol Head Neck Surg Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-06-29 Completed Date: 2007-08-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8508176 Medline TA: Otolaryngol Head Neck Surg Country: United States |
Other Details:
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Languages: eng Pagination: 130-7 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology-Head and Neck Surgery, Rambam Health Care Campus, Haifa, Israel. ariegor@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Biopsy, Fine-Needle Carcinoma, Squamous Cell / diagnosis Diagnosis, Differential Female Fluorodeoxyglucose F18 / diagnostic use* Follow-Up Studies Head and Neck Neoplasms / diagnosis* Humans Image Processing, Computer-Assisted / methods Male Middle Aged Patient Care Planning Positron-Emission Tomography / methods*, statistics & numerical data Predictive Value of Tests Prospective Studies Radiopharmaceuticals / diagnostic use* Sensitivity and Specificity Tomography, X-Ray Computed / methods*, statistics & numerical data Whole Body Imaging |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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