Document Detail

The role of B-mode ultrasonography and electron beam computed tomography in evaluation of Takayasu's arteritis: a study of 43 patients.
MedLine Citation:
PMID:  10966210     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate the capacity of B-Mode ultrasonography (B-Mode US) and electron-beam computed tomography (EBCT) to detect arterial changes in Takayasu's arteritis. METHODS: EBCT angiography of the thoracoabdominal aorta and pulmonary artery, and B-mode US of large superficial arteries (common carotid, subclavian, and common femoral arteries) were performed prospectively in 43 consecutive patients with established Takayasu's arteritis. The arterial wall thickness was measured, and lumen changes (stenosis, aneurysm) were noted. RESULTS: The combined results of B-Mode US and EBCT examinations showed that every patient had at least one abnormality at the studied sites. The median score of abnormal sites was 7. The most frequent lesion was a characteristic long, homogeneous, circumferential thickening, visualized in 52% of examined sites and in all patients but one (98%). Stenosis was detected by US and by EBCT, respectively, in 44% and 32% of patients, and aneurysm in 0.4% and 68%. CONCLUSIONS: In Takayasu's arteritis, B-Mode US and EBCT was able to visualize the classical caliber abnormalities (stenosis, aneurysm) and, in contrast to angiography, to depict vessel wall thickening, a major pathologic feature of the disease. Both these safe techniques seem more useful than angiography to characterize and map the vascular lesions of Takayasu's arteritis.
C Lefebvre; A Rance; J F Paul; C Beguin; O Bletry; Z Amoura; J C Piette; J N Fiessinger
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Seminars in arthritis and rheumatism     Volume:  30     ISSN:  0049-0172     ISO Abbreviation:  Semin. Arthritis Rheum.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-12-04     Completed Date:  2000-12-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1306053     Medline TA:  Semin Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  25-32     Citation Subset:  IM    
Service de Médecine, Interne Générale, Cliniques Universitaires Saint-Luc, Bruxelles, Belgique.
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MeSH Terms
Aneurysm / radiography,  ultrasonography
Constriction, Pathologic / radiography,  ultrasonography
Echocardiography, Doppler
Middle Aged
Prospective Studies
Takayasu Arteritis / radiography*,  ultrasonography*
Tomography, X-Ray Computed*

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