Document Detail


The role of Angiotensin-converting enzyme in blood pressure control, renal function, and male fertility.
MedLine Citation:
PMID:  18406804     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Angiotensin-converting enzyme (ACE) is a zinc peptidase that plays a major role in the renin-angiotensin system. In mammals, the enzyme is present as two isozymes: a somatic form involved in blood-pressure regulation and a testis form of unknown function. Mice lacking ACE have been created and shown to have low systolic blood pressures and defects in renal development and function. These mice also have reduced male fertility, implicating the testis isozyme in reproductive function. (Trends Endocrinol Metab 1997;8:181-186). (c) 1997, Elsevier Science Inc.
Authors:
C R Esther; E M Marino; K E Bernstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Trends in endocrinology and metabolism: TEM     Volume:  8     ISSN:  1043-2760     ISO Abbreviation:  Trends Endocrinol. Metab.     Publication Date:  1997 Jul 
Date Detail:
Created Date:  2008-04-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001516     Medline TA:  Trends Endocrinol Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  181-6     Citation Subset:  -    
Affiliation:
Department of Pathology, Emory University, Atlanta, Georgia 30322, USA.
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