| On the robustness of regular systems of inbreeding. | |
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MedLine Citation:
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PMID: 1804450 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Half-sib, first cousin, half nth cousin, and nth cousin mating systems are robust in that small deviations from the mating structure will not significantly alter the levels of genetic identity or effect qualitative distinctions between the models. Substitution of nearest kin in matings may either increase or decrease the level of homozygosity depending on the mating structure; the effect of a single error in the mating structure is not an accurate indicator of the equilibrium resulting from recurrent errors. Models of mixed half nth cousin or nth cousin mating show that the relative frequency of the lowest order inbred mating essentially determines the level of homozygosity. Any positive relative frequency of more distant matings will reduce the probability of identity by descent under half-sib or first cousin mating to less than 1. |
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Authors:
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R B Campbell |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Mathematical biosciences Volume: 104 ISSN: 0025-5564 ISO Abbreviation: Math Biosci Publication Date: 1991 Apr |
Date Detail:
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Created Date: 1992-05-04 Completed Date: 1992-05-04 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0103146 Medline TA: Math Biosci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-19 Citation Subset: IM |
Affiliation:
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Department of Mathematics and Computer Science, University of Northern Iowa, Cedar Falls 50614-0441. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alleles Animals Consanguinity* Homozygote Humans Inbreeding* Models, Genetic* Probability |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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