Document Detail

The risks and benefits of transseptal endocardial pacing.
MedLine Citation:
PMID:  22139700     Owner:  NLM     Status:  Publisher    
PURPOSE OF REVIEW: Transseptal endocardial left-ventricular pacing has a number of potential advantages over left-ventricular epicardial pacing from the coronary sinus, for implantation of cardiac resynchronization therapy (CRT) devices. In this study we review the risks and potential benefits. RECENT FINDINGS: Permanent transseptal endocardial pacing has been shown to be clinically feasible. Different methods have been described, including a superior, inferior or mixed approach. Endocardial pacing has a number of potential advantages over conventional left-ventricular pacing from the coronary sinus. It may be possible to achieve more effective CRT through optimizing the left-ventricular lead position, which is possible because of the greater choice of stimulation site. Endocardial rather than epicardial stimulation may result in more rapid ventricular activation and may be less arrhythmogenic. Disadvantages of this approach include the risk of thromboembolism and the potential for interaction with the mitral valve. SUMMARY: Transseptal endocardial left-ventricular pacing shows promise for use in cardiac resynchronization therapy. The safety and effectiveness of this technique should now be tested in larger clinical trials.
Zachary Whinnett; Pierre Bordachar
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-1
Journal Detail:
Title:  Current opinion in cardiology     Volume:  -     ISSN:  1531-7080     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8608087     Medline TA:  Curr Opin Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
aBordeaux University 2 bUniversity Hospital of Bordeaux, Bordeaux, France cImperial College London, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The effects of PLGA microparticles on intestinal absorption of p-glycoprotein substrate using the ev...
Next Document:  Sudden cardiac death in athletes: what is the role of screening?