Document Detail

The risk of unexplained antepartum stillbirth in second pregnancies following caesarean section in the first pregnancy.
MedLine Citation:
PMID:  18410656     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine if a previous caesarean section increases the risk of unexplained antepartum stillbirth in second pregnancies. STUDY DESIGN: Retrospective cohort study. SETTING: Large Canadian perinatal database. POPULATION: 158 502 second births. METHODS: Data were obtained from a large perinatal database, which supplied data on demographics, pregnancy complications, maternal medical conditions, previous caesarean section and pregnancy outcomes. MAIN OUTCOME MEASURES: Total and unexplained stillbirth. RESULTS: The antepartum stillbirth rate was 3.0/1000 in the previous caesarean section group compared with 2.7/1000 in the previous vaginal delivery group (P= 0.46). Multivariate logistic regression modelling, including terms for maternal age (polynomial), weight >91 kg, smoking during pregnancy, pre-pregnancy hypertension and diabetes, did not document an association between previous caesarean section and unexplained antepartum stillbirth (OR 1.27, 95% CI 0.92-1.77). CONCLUSION: Caesarean section in the first birth does not increase the risk of unexplained antepartum stillbirth in second pregnancies.
S L Wood; S Chen; S Ross; R Sauve
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  115     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-15     Completed Date:  2008-06-06     Revised Date:  2008-12-10    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  726-31     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Calgary, Foothills Hospital, Calgary, Alberta, Canada.
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MeSH Terms
Alberta / epidemiology
Cesarean Section / adverse effects*
Epidemiologic Methods
Maternal Age
Pregnancy Complications / epidemiology*,  etiology
Premature Birth / epidemiology
Stillbirth / epidemiology*
Comment In:
BJOG. 2008 Oct;115(11):1458; author reply 1458-9   [PMID:  18823493 ]
BJOG. 2008 Sep;115(10):1324; author reply 1325-6   [PMID:  18715426 ]
BJOG. 2008 Sep;115(10):1324-5; author reply 1325-6   [PMID:  18715425 ]

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