Document Detail


A risk prediction model for severe intraventricular hemorrhage in very low birth weight infants and the effect of prophylactic indomethacin.
MedLine Citation:
PMID:  24113396     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Develop a risk prediction model for severe intraventricular hemorrhage (IVH) in very low birth weight infants (VLBWI).
STUDY DESIGN: Prospectively collected data of infants with birth weight 500 to 1249 g born between 2001 and 2010 in centers from the Neocosur Network were used. Forward stepwise logistic regression model was employed. The model was tested in the 2011 cohort and then applied to the population of VLBWI that received prophylactic indomethacin to analyze its effect in the risk of severe IVH.
RESULT: Data from 6538 VLBWI were analyzed. The area under ROC curve for the model was 0.79 and 0.76 when tested in the 2011 cohort. The prophylactic indomethacin group had lower incidence of severe IVH, especially in the highest-risk groups.
CONCLUSION: A model for early severe IVH prediction was developed and tested in our population. Prophylactic indomethacin was associated with a lower risk-adjusted incidence of severe IVH.
Authors:
M J Luque; J L Tapia; L Villarroel; G Marshall; G Musante; W Carlo; J Kattan;
Related Documents :
23259876 - Neonatal morbidity mortality outcomes in pre-term premature rupture of membranes.
24358596 - The impact of breastfeeding on body weight.
11335736 - Randomized trial of nasal synchronized intermittent mandatory ventilation compared with...
24499636 - Role of antenatal care and iron supplementation during pregnancy in preventing low birt...
19812586 - Prevalence of renal anomalies after urinary tract infections in hospitalized infants le...
17168976 - Prediction of transfusions in extremely low-birthweight infants in the erythropoietin era.
Publication Detail:
Type:  Journal Article     Date:  2013-10-10
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  34     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2013-12-30     Completed Date:  2014-08-13     Revised Date:  2014-11-10    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  43-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
Cerebral Hemorrhage* / prevention & control
Female
Humans
Incidence
Indomethacin / therapeutic use*
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight*
Logistic Models
Male
ROC Curve
Risk Assessment / methods*
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; XXE1CET956/Indomethacin
Investigator
Investigator/Affiliation:
Guillermo Colantonio / ; Jorge Zapata / ; Gaston Perez / ; Susana Garcia Ana Pedraza / ; Isabel Kurlat / ; Oscar Di Siervi / ; Adriana Escarate / ; Gonzalo Mariani / ; Jose Maria Ceriani / ; Silvia Fernandez / ; Carlos Fustiñana / ; Pablo Brener / ; Eleonora Edwards / ; Jorge Tavosnaska / ; Liliana Roldan / ; Hector Sexer / ; Gladys Saa / ; Debora Sabatelli / ; Maria Laura Gendra / ; Maria Fernanda Buraschi / ; Paula Molina / ; Daniel Agost / ; Federico Morganti / ; Adriana Fontana / ; Daniela Chandias / ; Monica Rinaldi / ; Carlos Grandi / ; Elio Rojas / ; Claudio Solana / ; Ricardo Nieto / ; Javier Meritano / ; Miguel Larguia / ; Laura Kasten / ; Lucrecia Cuneo / ; Marcelo Decaro / ; Lionel Cracco / ; Gustavo Bassi / ; Noemi Jacobi / ; Andrea Brum / ; Nestor Vain / ; Adriana Aguilar / ; Miriam Guerrero / ; Edgardo Szyld / ; Alcira Escandar / ; Daniel Abdala / ; Martin Guida / ; Lucila Ferrin / ; Horacio Roge / ; Gabriel Musante / ; Maria C Capelli / ; Juan Pablo Berazategui / ; Magdalena de Elizalde / ; Juan Ignacio Fraga / ; Rodolfo Keller / ; Luis Ahumada / ; Mirta Ferreyra / ; Vanda Ferreira / ; Roberta Borges / ; Marynea Do Vale / ; Silvia Cavalcante / ; Joama Gusmão / ; Patricia Franco / ; Maria Jose Silva / ; Jorge Fabres / ; Alberto Estay / ; Alvaro Gonzalez / ; Jose Luis Tapia / ; Javier Kattan / ; Mariela Quezada / ; Soledad Urzua / ; Rodrigo Ramirez / ; Maria Eugenia Hübner / ; Jaime Burgos / ; Jorge Catalan / ; Lilia Campos / ; Lilian Cifuentes / ; Jorge Leon / ; Roxana Aguilar / ; Sergio Treuer / ; Jimena Giaconi / ; Aldo Bancalari / ; Jane Standen / ; Marisol Escobar / ; Viviana Veas / ; Daniela Sandino / ; Agustina Gonzalez / ; Claudia Avila / ; Carla Guzman / ; Claudia Toro / ; Patricia Mena / ; Beatriz Milet / ; Enrica Pittaluga / ; Veronica Peña / ; Rafael Mendizabal / ; Dagoberto Pizarro / ; Ivonne D'Apremont / ; Guillermo Marshall / ; Luis Villarroel / ; Mariela Quezada / ; Angelica Dominguez / ; Jose Lacarruba / ; Elizabeth Cespedes / ; Ramon Mir / ; Elvira Mendieta / ; Larissa Genes / ; Carlos Caballero / ; Veronica Webb / ; Fabiola Rivera / ; Margarita Llontop / ; Sicilia Bellomo / ; Jaime Zegarra / ; Oscar Chumbes / ; Anne Castañeda / ; Walter Cabrera / ; Raul Llanos / ; Jorge Mucha / ; Gustavo Garcia / ; Beatriz Ceruti / ; Daniel Borbonet / ; Sandra Gugliucci / ; Ana Lain / ; Mariza Martinez / ; Gabriela Bazan / ; Susana Piffaretti / ; Isabel Cuña / ; Patricia Bermudez /
Comments/Corrections
Comment In:
J Perinatol. 2014 Oct;34(10):802   [PMID:  25263729 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Disease progression by infecting HIV-1 subtype in a seroconverter cohort in sub-Saharan Africa.
Next Document:  Neonatal isolated rectal bleeding and the risk of hypersensitivity syndromes.