Document Detail

The risk of impending preterm delivery in asymptomatic patients with a nonmeasurable cervical length in the second trimester.
MedLine Citation:
PMID:  20659728     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to determine the pregnancy outcome of asymptomatic patients in the second trimester with a nonmeasurable cervical length (0 mm).
STUDY DESIGN: This retrospective cohort study included 78 patients with singleton pregnancies and a sonographic nonmeasurable cervix that was detected at 14-28 weeks of gestation. Patients with cervical cerclage were excluded.
RESULTS: We found that (1) 75.3% of the patients delivered before 32 weeks of gestation; (2) the median diagnosis-to-delivery interval was 20.5 days, and the delivery rate within 7 and 14 days was 28.2% and 35.6%, respectively; and (3) patients with a nonmeasurable cervix that was diagnosed at <24 weeks of gestation had a shorter median diagnosis-to-delivery interval than patients who were diagnosed at 24-28 weeks of gestation (17.5 vs 41 days; P = .009).
CONCLUSION: Asymptomatic women with a nonmeasurable cervix in the second trimester have a median diagnosis-to-delivery interval of approximately 3 weeks. Almost 65% of these patients will not deliver within 2 weeks, yet 75% of them will deliver before 32 weeks of gestation. The earlier a nonmeasurable cervix is identified, the shorter the diagnosis-to-delivery interval.
Edi Vaisbuch; Roberto Romero; Shali Mazaki-Tovi; Offer Erez; Juan Pedro Kusanovic; Pooja Mittal; Francesca Gotsch; Clara Ward; Vivian Romero; Tinnakorn Chaiworapongsa; Percy Pacora; Lami Yeo; Sonia S Hassan
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural     Date:  2010-07-24
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  203     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  2010-12-06     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  446.e1-9     Citation Subset:  AIM; IM    
Copyright Information:
Published by Mosby, Inc.
Perinatology Research Branch, Intramural Division, National Institute of Child Health and Human Development/NIH/DHHS, Bethesda, MD 20892, USA.
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MeSH Terms
Cervical Length Measurement*
Cervix Uteri / ultrasonography*
Kaplan-Meier Estimate
Logistic Models
Obstetric Labor, Premature*
Pregnancy Trimester, Second
Retrospective Studies
Ultrasonography, Prenatal
Grant Support
Comment In:
Am J Obstet Gynecol. 2010 Nov;203(5):416-7   [PMID:  21055509 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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