| The right ventricle in sepsis. | |
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MedLine Citation:
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PMID: 18954701 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Right ventricular dysfunction is common in sepsis and septic shock because of decreased myocardial contractility and elevated pulmonary vascular resistance despite a concomitant decrease in systemic vascular resistance. The mainstay of treatment for acute right heart failure includes treating the underlying cause of sepsis and reversing circulatory shock to maintain tissue perfusion and oxygen delivery. Decreasing pulmonary vascular resistance with selective pulmonary vasodilators is a reasonable approach to improving cardiac output in septic patients with right ventricular dysfunction. Treatment for right ventricular dysfunction in the setting of sepsis should concentrate on fluid repletion, monitoring for signs of RV overload, and correction of reversible causes of elevated pulmonary vascular resistance, such as hypoxia, acidosis, and lung hyperinflation. |
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Authors:
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Chee M Chan; James R Klinger |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinics in chest medicine Volume: 29 ISSN: 1557-8216 ISO Abbreviation: Clin. Chest Med. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-10-28 Completed Date: 2009-03-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7907612 Medline TA: Clin Chest Med Country: United States |
Other Details:
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Languages: eng Pagination: 661-76, ix Citation Subset: IM |
Affiliation:
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Division of Pulmonary and Critical Care Medicine, Washington Hospital Center, 110 Irving Street NW #2B-39, Washington, DC 20010, USA. chee.m.chan@medstar.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology Blood Volume / physiology Critical Care / methods Humans Myocardial Contraction / physiology Sepsis / physiopathology* Shock, Septic / physiopathology* Systole / physiology Vascular Resistance / physiology Ventricular Dysfunction, Right / physiopathology* Ventricular Function, Left / physiology Ventricular Function, Right / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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