Document Detail

A revised measure of acute pain in infants.
MedLine Citation:
PMID:  7561228     Owner:  NLM     Status:  MEDLINE    
Acute pain in infants is not assessed or managed optimally. The objectives of the study were (a) to adapt a behavioral pain assessment measure (Children's Hospital of Eastern Ontario Pain Scale, CHEOPS) for use with infants, and (b) to establish the reliability and validity of the measure in a study of infants undergoing immunization. Ninety-six healthy 4- to 6-month-old infants were randomized to receive either the local anesthetic cream Eutectic Mixture of Local Anesthetics (EMLA) (N = 49), or a placebo (N = 47) prior to immunization. The infant's behavioral response was videotaped immediately before and following the immunization. Postprocedural pain scores were assessed from the videotape and were significantly lower in infants who received EMLA (P = 0.01). Pain scores were also significantly correlated with visual analogue scale (VAS) scores assessed during vaccination. Five independent raters also independently rated ten infants to determine interrater reliability. Agreement between raters' scores was high (intraclass correlation coefficient, 0.95). Results from this study suggest that this measure has beginning construct and concurrent validity and interrater reliability when used in a research study. Further testing of the measure in the clinical setting is required.
A Taddio; I Nulman; B S Koren; B Stevens; G Koren
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of pain and symptom management     Volume:  10     ISSN:  0885-3924     ISO Abbreviation:  J Pain Symptom Manage     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-11-13     Completed Date:  1995-11-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8605836     Medline TA:  J Pain Symptom Manage     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  456-63     Citation Subset:  IM    
Division of Clinical Pharmacology, Hospital for Sick Children, Toronto, Ontario, Canada.
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MeSH Terms
Acute Disease
Double-Blind Method
Pain Measurement / methods*
Vaccination / adverse effects

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