Document Detail


A review of the treatment guidelines on the management of low levels of high-density lipoprotein cholesterol.
MedLine Citation:
PMID:  15103174     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper aims to review the guidelines on the importance given to high-density lipoprotein cholesterol (HDL-C) as a risk factor or as threshold and target level in the treatment of dyslipidemia. We developed a strategy with cholesterol-related key words to search for guidelines in the major databases. The Appraisal of Guidelines Research Evaluation (AGREE) instrument was used for the evaluation and inclusion of the guidelines. In total nine guidelines were selected. Almost all selected guidelines consider low HDL-C as a marker of an increased risk for coronary heart disease. However, only few guidelines use the level of HDL-C as a threshold or target level for the treatment of dyslipidemia. The guidelines provide only little information on the management of patients with treatment-induced low HDL-C. Instead of using total cholesterol (TC) or low-density lipoprotein cholesterol (LDL-C) we consider the use of the ratios of TC to HDL-C or LDL-C to HDL-C as a threshold as well as a target for treatment.
Authors:
Dirk Devroey; Karolien Vantomme; Willem Betz; Jan Vandevoorde; Jan Kartounian
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Publication Detail:
Type:  Journal Article; Review     Date:  2004-04-19
Journal Detail:
Title:  Cardiology     Volume:  102     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  2004  
Date Detail:
Created Date:  2004-07-06     Completed Date:  2004-10-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  61-6     Citation Subset:  IM    
Copyright Information:
Copyright 2004 S. Karger AG, Basel
Affiliation:
Department of General Practice, University of Brussels, Brussels, Belgium. dirk.devroey@vub.ac.be
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MeSH Terms
Descriptor/Qualifier:
Cholesterol, HDL / blood*
Coronary Disease / blood*,  etiology
Humans
Hyperlipidemias / blood,  complications*
Practice Guidelines as Topic
Risk Factors
Chemical
Reg. No./Substance:
0/Cholesterol, HDL
Comments/Corrections
Comment In:
Cardiology. 2005;103(4):199-200   [PMID:  15832027 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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