Document Detail

A review of systemic retinoid therapy for acne and related conditions.
MedLine Citation:
PMID:  15037925     Owner:  NLM     Status:  MEDLINE    
Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the "gold standard" in the treatment of acne and its variants. This is the only approach to acne with the possibility of a permanent "cure" or long term remission. The role of isotretinoin has evolved with higher dosage schedules and use earlier in the course of the disease. The frequency of laboratory monitoring has diminished along with associated costs based on 2 decades of experience. Pregnancy-associated safeguards have become a more prominent facet of oral retinoid therapy leading to increased safety for its use in females of child-bearing potential.
R A Kunynetz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Skin therapy letter     Volume:  9     ISSN:  1201-5989     ISO Abbreviation:  Skin Therapy Lett.     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-03-23     Completed Date:  2004-04-23     Revised Date:  2005-06-30    
Medline Journal Info:
Nlm Unique ID:  9891441     Medline TA:  Skin Therapy Lett     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  1-4     Citation Subset:  IM    
Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Acne Vulgaris / drug therapy*
Isotretinoin / administration & dosage,  adverse effects,  therapeutic use*
Treatment Outcome
Reg. No./Substance:
Erratum In:
Skin Therapy Lett. 2005 Mar;10(2):9

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