Document Detail

A review of studies on maternal occupational exposures and birth defects, and the limitations associated with these studies.
MedLine Citation:
PMID:  11463868     Owner:  NLM     Status:  MEDLINE    
The proportion of pregnant women who work during pregnancy is increasing as more women move into previously male-dominated occupations. With this move, occupational exposure to chemical or physical factors during pregnancy could be further increased. In the last decade, there have been many reports on the causes of birth defects. Unfortunately, most reported associations between occupational exposures and adverse reproductive outcomes in epidemiological studies are equivocal and often controversial. Many reported associations are only suggestive. More information is needed before firm conclusions can be drawn. The major reasons for ambiguous findings are due to limitations of study methodology, e.g. inappropriate endpoints, multiple confounders, low study power and inadequate analysis methods. It must also be noted that maternal work, and therefore exposure, may also differ greatly from country to country.
L Shi; S E Chia
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Occupational medicine (Oxford, England)     Volume:  51     ISSN:  0962-7480     ISO Abbreviation:  Occup Med (Lond)     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-20     Completed Date:  2001-08-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9205857     Medline TA:  Occup Med (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  230-44     Citation Subset:  IM    
Department of Community, Occupational & Family Medicine, Faculty of Medicine, National University of Singapore, Singapore, Republic of Singapore.
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MeSH Terms
Bias (Epidemiology)
Congenital Abnormalities / etiology*
Data Collection / methods
Maternal Exposure / adverse effects*
Occupational Exposure / adverse effects*
Risk Factors

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