Document Detail

A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction.
MedLine Citation:
PMID:  19926374     Owner:  NLM     Status:  MEDLINE    
Opioid dependence is a problem of national concern, especially with dramatically increased rates of abuse and dependence of prescription opioids. The current article provides an up-to-date review of the literature on opioid dependence treatment, with a focus on conclusions drawn by experts in the field (e.g., Cochrane reviews and meta-analyses) and methodologically rigorous studies (e.g., randomized controlled trials). We describe the major classes of drug treatments available, including opioid agonist (e.g., methadone, buprenorphine, LAAM), antagonist (e.g., naltrexone) and non-opioid pharmacotherapies (e.g., alpha2 adrenergic agonists). These treatments are discussed in the context of detoxification and long term treatment options such as abstinence-based and maintenance strategies. We review the state of the literature as to prevention of opioid overdose and discuss the widespread problem of comorbidity among opioid-dependent populations. We also focus prominently on evidence for inclusion of psychosocial approaches in treatment regimens, either as stand-alone or in conjunction with psychopharmacological options.
Jennifer C Veilleux; Peter J Colvin; Jennifer Anderson; Catherine York; Adrienne J Heinz
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-10-30
Journal Detail:
Title:  Clinical psychology review     Volume:  30     ISSN:  1873-7811     ISO Abbreviation:  Clin Psychol Rev     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-04-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8111117     Medline TA:  Clin Psychol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  155-66     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
University of Illinois at Chicago, 1007 W Harrison Street, M/C 285, Chicago, IL 60607, USA.
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MeSH Terms
Adrenergic Agents / therapeutic use
Biofeedback, Psychology
Cognitive Therapy
Narcotic Antagonists / therapeutic use*
Narcotics / therapeutic use*
Opioid-Related Disorders / epidemiology*,  therapy*
Self-Help Groups
Reg. No./Substance:
0/Adrenergic Agents; 0/Narcotic Antagonists; 0/Narcotics

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