| A review of mortality due to Clostridium difficile infection. | |
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MedLine Citation:
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PMID: 20361997 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this review we examine published literature to ascertain mortality in relation to Clostridium difficile infection (CDI) and the factors associated with mortality. In the 27 studies that had sufficient data, there were 10975 cases of CDI with great heterogeneity in the methods for reporting mortality. We calculated the overall associated mortality to be at least 5.99% within 3 months of diagnosis. The most important finding is that higher mortality is associated with advanced age, being 13.5% in patients over 80 years. Studies performed after 2000 had a significantly higher mortality than those before this date. We propose minimum standards for reporting mortality in future studies. |
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Authors:
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J A Karas; D A Enoch; S H Aliyu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-03-31 |
Journal Detail:
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Title: The Journal of infection Volume: 61 ISSN: 1532-2742 ISO Abbreviation: J. Infect. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-10-07 Revised Date: 2013-05-20 |
Medline Journal Info:
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Nlm Unique ID: 7908424 Medline TA: J Infect Country: England |
Other Details:
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Languages: eng Pagination: 1-8 Citation Subset: IM |
Copyright Information:
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Copyright (c) 2010 The British Infection Society. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Clinical Microbiology & Public Health Laboratory, Health Protection Agency, Box 236, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK. andreas.karas@papworth.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Age Factors Aged Aged, 80 and over Clostridium difficile / isolation & purification* Enterocolitis, Pseudomembranous / mortality* Female Humans Male Middle Aged Risk Factors Young Adult |
| Comments/Corrections | |
Comment In:
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J Infect. 2013 Jan;66(1):111-3
[PMID:
23103665
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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