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A review of epidemiological studies on neuropsychological effects of air pollution.
MedLine Citation:
PMID:  22252905     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The aim of the present review is to provide an update of the epidemiological evidence of the effects of air pollution on neuropsychological development and impairment, as well as of the evidence on individual susceptibility to these effects. Animal studies have shown deposition of ultrafine particles containing metals in olfactory bulb and frontal cortical and subcortical areas, and overexpression of inflammatory responses, white matter lesions and vascular pathology in these areas that could be the basis for functional and structural brain effects. Several observational studies in the general population have observed cognitive deficits and behavioural impairment in children and the elderly. These effects, however, are not conclusive given the limited number of studies, their small size and their methodological constraints.
Authors:
M Guxens; J Sunyer
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Publication Detail:
Type:  Journal Article     Date:  2012-01-03
Journal Detail:
Title:  Swiss medical weekly     Volume:  141     ISSN:  1424-3997     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2012  
Date Detail:
Created Date:  2012-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  w13322     Citation Subset:  IM    
Affiliation:
Centre for Research in Environmental Epidemiology (CREAL), Carrer Dr. Aiguader 88, 08003-Barcelona, ES.
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