Document Detail

A review of dietary and non-dietary exposure to bisphenol-A.
MedLine Citation:
PMID:  22889897     Owner:  NLM     Status:  Publisher    
Due to the large number of applications of bisphenol-A (BPA), the human exposure routes are multiple. We aimed to review shortly the food and non-food sources of BPA, and to evaluate their contribution to the human exposure. Food sources discussed here include epoxy resins, polycarbonate and other applications, such as paperboard and polyvinylchloride materials. Among the non-food sources, exposures through dust, thermal paper, dental materials, and medical devices were summarized. Based on the available data for these exposure sources, it was concluded that the exposure to BPA from non-food sources is generally lower than that from exposure from food by at least one order of magnitude for most studied subgroups. The use of urinary concentrations from biomonitoring studies was evaluated and the back-calculation of BPA intake seems reliable for the overall exposure assessment. In general, the total exposure to BPA is several orders of magnitude lower than the current tolerable daily intake of 50μg/kgbw/day. Finally, the paper concludes with some critical remarks and recommendations on future human exposure studies to BPA.
Tinne Geens; Dominique Aerts; Carl Berthot; Jean-Pierre Bourguignon; Leo Goeyens; Philippe Lecomte; Guy Maghuin-Rogister; Anne-Madeleine Pironnet; Luc Pussemier; Marie-Louise Scippo; Joris Van Loco; Adrian Covaci
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-4
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  -     ISSN:  1873-6351     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ltd.
Toxicological Centre, University of Antwerp, Universiteitsplein 1, Antwerp, Belgium; Belgian Superior Health Council, FPS Health, Food Chain Safety and Environment, Rue de l'Autonomie 4, 1070 Brussels, Belgium.
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