| A review of the biostability and carcinogenicity of polyurethanes in medicine and the new generation of 'biostable' polyurethanes. | |
| | |
MedLine Citation:
|
PMID: 7986779 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Polyurethanes are very versatile materials which have been used in the body for over 20 years. In fact, there are probably more scientific papers describing these materials and modifications of these materials for medical use than any other material to date. Unfortunately, some formulations of these polymers are subject to biodegradation and have limited their application in the body. Extensive investigation of the biodegradation mechanisms of these polymers by many researchers in the field has led to the development of a new generation of what are now called 'biostable' polyurethanes. This article reviews the history of polyurethane in medicine, polyurethane nomenclature, the biodegradation of these materials, the proposed mechanisms of its degradation as well as the carcinogenicity associated with these materials. Included in the discussion are the polyurethanes used as pacemaker lead insulators as well as those used to coat breast implants. The article concludes with a review of the new generation of 'biostable' polyurethanes and their proposed formulations. |
| | |
Authors:
|
L Pinchuk |
Related Documents
:
|
21062149 - Baubles, bangles, and biotypes: a critical review of the use and abuse of the biotype c... 11443379 - Adaptive management on public lands in the united states: commitment or rhetoric? 19573269 - What are the real risks of sport-related concussion, and are they modifiable? 10295659 - The librarian as consultant and educator for personal file management software. 8315359 - Homeopathy. 12222589 - Practice effects on speech production planning: evidence from slips of the tongue in sp... 1127389 - The first-year family practice resident. an identity crisis. 22241089 - Barriers to integrating personalized medicine into clinical practice: a best-worst scal... 11519629 - Challenges in the transfer of contingency management techniques: comment on silverman e... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Journal of biomaterials science. Polymer edition Volume: 6 ISSN: 0920-5063 ISO Abbreviation: J Biomater Sci Polym Ed Publication Date: 1994 |
Date Detail:
|
Created Date: 1995-01-11 Completed Date: 1995-01-11 Revised Date: 2008-02-20 |
Medline Journal Info:
|
Nlm Unique ID: 9007393 Medline TA: J Biomater Sci Polym Ed Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 225-67 Citation Subset: IM |
Affiliation:
|
Corvita Corporation, Miami, FL 33122. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Biocompatible Materials / adverse effects*, toxicity Biodegradation, Environmental Carcinogenicity Tests Cations / metabolism Female Foreign-Body Reaction Humans Hydrolysis Male Mice Molecular Structure Molecular Weight Neoplasms / chemically induced* Neoplasms, Experimental / chemically induced Oxidation-Reduction Polyurethanes / adverse effects*, chemistry, classification, toxicity Prostheses and Implants / adverse effects* Rats Species Specificity Stress, Mechanical |
| Chemical | |
Reg. No./Substance:
|
0/Biocompatible Materials; 0/Cations; 0/Polyurethanes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Educational Family Therapy for schizophrenia: a new treatment model for clinical service and researc...
Next Document: The adsorption of F(ab')2 on positively and negatively charged polystyrene beads.