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A review of antimalarial plants used in traditional medicine in communities in Portuguese-Speaking countries: Brazil, Mozambique, Cape Verde, Guinea-Bissau, São Tomé and Príncipe and Angola.
MedLine Citation:
PMID:  21881769     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The isolation of bioactive compounds from medicinal plants, based on traditional use or ethnomedical data, is a highly promising potential approach for identifying new and effective antimalarial drug candidates. The purpose of this review was to create a compilation of the phytochemical studies on medicinal plants used to treat malaria in traditional medicine from the Community of Portuguese-Speaking Countries (CPSC): Angola, Brazil, Cape Verde, Guinea-Bissau, Mozambique and São Tomé and Príncipe. In addition, this review aimed to show that there are several medicinal plants popularly used in these countries for which few scientific studies are available. The primary approach compared the antimalarial activity of native species used in each country with its extracts, fractions and isolated substances. In this context, data shown here could be a tool to help researchers from these regions establish a scientific and technical network on the subject for the CPSC where malaria is a public health problem.
Authors:
Jefferson Rocha de A Silva; Aline de S Ramos; Marta Machado; Dominique F de Moura; Zoraima Neto; Marilene M Canto-Cavalheiro; Paula Figueiredo; Virgilio E do Rosário; Ana Claudia F Amaral; Dinora Lopes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Memórias do Instituto Oswaldo Cruz     Volume:  106 Suppl 1     ISSN:  1678-8060     ISO Abbreviation:  Mem. Inst. Oswaldo Cruz     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-09-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7502619     Medline TA:  Mem Inst Oswaldo Cruz     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  142-58     Citation Subset:  IM    
Affiliation:
Laboratório de Cromatografia, Departamento de Química, Universidade Federal do Amazonas, Manaus, AM, Brasil.
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