Document Detail

A review of anti-infective and anti-inflammatory chalcones.
MedLine Citation:
PMID:  17112640     Owner:  NLM     Status:  MEDLINE    
Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants, and have also been shown to display a diverse array of pharmacological activities. The purpose of this review is to provide an overview of the pharmacological activity of synthetic and naturally occurring chalcones. This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.
Zdzisława Nowakowska
Publication Detail:
Type:  Journal Article; Review     Date:  2006-11-15
Journal Detail:
Title:  European journal of medicinal chemistry     Volume:  42     ISSN:  0223-5234     ISO Abbreviation:  Eur J Med Chem     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-02-26     Completed Date:  2007-05-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0420510     Medline TA:  Eur J Med Chem     Country:  France    
Other Details:
Languages:  eng     Pagination:  125-37     Citation Subset:  IM    
Department of Chemistry, Adam Mickiewicz University, Grunwaldzka, Poznań, Poland. <>
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MeSH Terms
Anti-Infective Agents* / chemistry,  pharmacology
Anti-Inflammatory Agents* / chemistry,  pharmacology
Chalcones* / chemistry,  pharmacology
Structure-Activity Relationship
Reg. No./Substance:
0/Anti-Infective Agents; 0/Anti-Inflammatory Agents; 0/Chalcones

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