Document Detail


A reversible fluorescent Hg2+ chemosensor based on a receptor composed of a thiol atom and an alkene moiety for living cell fluorescence imaging.
MedLine Citation:
PMID:  20567789     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A novel reversible fluorescence turn-on chemosensor 1 for Hg(2+) was constructed based on a new receptor composed of an S atom and an alkene moiety. The sensor showed a large fluorescence enhancement response (1000-fold enhancement), high selectivity, and high sensitivity with a detection limit of 27.5 nM. Significantly, the reversible sensor functioned well in the near pure aqueous medium and could be employed for Hg(2+) imaging in living cells.
Authors:
Weiying Lin; Xiaowei Cao; Yundi Ding; Lin Yuan; Quanxing Yu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-21
Journal Detail:
Title:  Organic & biomolecular chemistry     Volume:  8     ISSN:  1477-0539     ISO Abbreviation:  Org. Biomol. Chem.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-29     Completed Date:  2010-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101154995     Medline TA:  Org Biomol Chem     Country:  England    
Other Details:
Languages:  eng     Pagination:  3618-20     Citation Subset:  IM    
Affiliation:
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China. weiyinglin@hnu.cn
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MeSH Terms
Descriptor/Qualifier:
Alkenes / chemistry*
Cations, Divalent / chemistry
Fluorescent Dyes / analysis*,  chemistry
Magnetic Resonance Spectroscopy
Mercury / analysis*,  chemistry
Molecular Structure
Spectrometry, Fluorescence
Sulfhydryl Compounds / chemistry*
Chemical
Reg. No./Substance:
0/Alkenes; 0/Cations, Divalent; 0/Fluorescent Dyes; 0/Sulfhydryl Compounds; 7439-97-6/Mercury

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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