Document Detail

A retrospective clinical and angiographic study of the coiling outcome of ruptured intracranial aneurysms.
MedLine Citation:
PMID:  20080410     Owner:  NLM     Status:  MEDLINE    
Many factors that determine the outcome of endovascular treatment of ruptured intracranial aneurysms are still controversial. We conducted a retrospective study of 203 patients with ruptured aneurysms treated by coiling to assess these factors. The Glasgow Outcome Scale score was used for clinical follow-up and magnetic resonance angiography for angiographic follow-up. Overall outcome and pretreatment variables predicting outcome were thoroughly analyzed. Good clinical grade on presentation was correlated with a better clinical outcome (p<0.001); however, symptomatic vasospasm (15.8% of patients) was correlated with a worse clinical outcome (p<0.001). Six patients (3%) suffered ischemic complications at the time of treatment, hemorrhagic events occurred in five patients (2.5%), permanent morbidity in five patients (2.5%) and overall mortality in 5.4%. In this series, we studied some factors currently debated in the literature and concluded that elderly patients (> or =65 years) with aneurysmal subarachnoid hemorrhage can safely be treated with endovascular therapy with a favorable outcome and that middle cerebral artery aneurysms can be safely embolized with results comparable to other locations.
Mostafa Saleh Melake; Munetaka Yamamoto; Kensaku Yoshida; Hidenori Oishi; Hajime Arai; Mohamed Elwan; Mohamed Okda; Wafik El-Sheikh; Tomokatsu Hori
Publication Detail:
Type:  Journal Article     Date:  2010-01-18
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  17     ISSN:  1532-2653     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  328-33     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ltd. All rights reserved.
Neurosurgery Department, Neurological Institute, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan.
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MeSH Terms
Aged, 80 and over
Aneurysm, Ruptured / mortality,  radiography*,  surgery*
Chi-Square Distribution
Embolization, Therapeutic / methods
Follow-Up Studies
Glasgow Outcome Scale
Headache / etiology
Intracranial Aneurysm / mortality,  radiography*,  surgery*
Magnetic Resonance Angiography / adverse effects*
Middle Aged
Outcome Assessment (Health Care)
Retrospective Studies
Statistics, Nonparametric
Vasospasm, Intracranial / etiology

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