Document Detail

A retrospective analysis of the management of freckles and lentigines using four different pigment lasers on Asian skin.
MedLine Citation:
PMID:  22372516     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The risk of post-inflammatory hyperpigmentation (PIH) is increased during freckles and lentigines treatment in Asians.
OBJECTIVE: To determine the effectiveness and safety of using 595-nm long pulsed dye laser (LPDL), 755-nm LP Alexandrite laser, 532-nm QS Nd:YAG laser and 532-nm LP potassium-titanyl-phosphate (KTP) laser for the treatment of freckles or lentigines in Asian patients.
METHODS: This is a retrospective study of 40 Chinese patients, who were divided into four groups based on treatment modality using four different pigment lasers. Each patient attended between 1 and 4 treatments (mean of 1.8), at 4-6 weeks intervals, depending on clinical response. Lesional clearance and PIH were assessed by two independent clinicians.
RESULTS: Statistically significant improvement of global and focal facial pigmentation was found after treatment with LPDL, QS Nd:YAG and LP KTP lasers. No significant improvement was found after LP Alexandrite laser. PIH risk was 20% after LP Alexandrite treatment, 10% with QS Nd:YAG, and absent after LPDL and LP KTP treatment.
CONCLUSION: A long pulse laser and small spot size appear to reduce the risks of lentigines treatment in darker skin types.
S G Y Ho; N P Y Chan; C K Yeung; S Y Shek; T Kono; H H L Chan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology     Volume:  14     ISSN:  1476-4180     ISO Abbreviation:  J Cosmet Laser Ther     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-30     Completed Date:  2012-08-16     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101136419     Medline TA:  J Cosmet Laser Ther     Country:  England    
Other Details:
Languages:  eng     Pagination:  74-80     Citation Subset:  IM    
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MeSH Terms
Asian Continental Ancestry Group*
Hyperpigmentation / ethnology,  etiology
Lasers, Dye / adverse effects,  therapeutic use*
Lasers, Solid-State / adverse effects,  therapeutic use*
Lentigo / ethnology,  therapy
Melanosis / ethnology,  therapy*
Middle Aged
Retrospective Studies
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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