Document Detail

Is retinopathy of prematurity increasing among infants less than 1250 g birth weight?
MedLine Citation:
PMID:  14647167     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Retinopathy of prematurity (ROP) is a complication seen in many very low birth weight infants. Severe ROP has been called a "marker" for severe disability. The purpose of this study was to evaluate the occurrence and severity of ROP among infants < or =1250 g birth weight treated in the Special Care Nursery at Women & Infants' Hospital over a period of 7 years from 1994 to 2000. STUDY DESIGN: This was a retrospective review of ROP data combined with neonatal follow-up data. Of the 1002 infants born with birth weights <1250 g, ophthalmologic data were available for 739 of 839 survivors. Analysis of variance and chi2 along with logistic regression were used to analyze outcomes. RESULTS: An increase in the overall occurrence of ROP was identified (40% to 54% linear trend, p=0.007). The occurrence of threshold ROP ranged from 2% to 5% (NS). Infants at greatest risk of ROP were those micropremies with birth weights <750 g (p<0.001). CONCLUSION: Severe ROP continues to be a significant morbidity among infants <750 g.
Maureen T O'Connor; Betty R Vohr; Richard Tucker; William Cashore
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  23     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2003-12-03     Completed Date:  2004-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  673-8     Citation Subset:  IM    
Department of Pediatrics, Women and Infants' Hospital, Brown Medical School, Providence, RI 02905, USA.
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MeSH Terms
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight*
Logistic Models
Oxygen Inhalation Therapy
Retinopathy of Prematurity / epidemiology*,  therapy
Retrospective Studies

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