| Is retinoic acid an endogenous ligand during urodele limb regeneration? | |
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MedLine Citation:
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PMID: 8877456 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of retinoids on a regenerating urodele limb make them interesting candidates for endogenous ligands during regeneration. We review the evidence for considering this possibility. This includes analysis of retinoids and retinoic acid receptors in the regenerate, and studies on activation of retinoid reporter genes. Recent work has provided evidence that the wound epidermis is a source of 9-cis retinoic acid, and may be a favorable model for studying the synthesis and release of this modulator. |
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Authors:
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C M Viviano; J P Brockes |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The International journal of developmental biology Volume: 40 ISSN: 0214-6282 ISO Abbreviation: Int. J. Dev. Biol. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1997-02-19 Completed Date: 1997-02-19 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8917470 Medline TA: Int J Dev Biol Country: SPAIN |
Other Details:
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Languages: eng Pagination: 817-22 Citation Subset: IM |
Affiliation:
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Ludwig Institute for Cancer Research, University College London, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Epidermis / cytology Extremities / physiology* Genes, Reporter Receptors, Retinoic Acid / metabolism Regeneration* Retinoids / metabolism Tretinoin / metabolism* Urodela / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Retinoic Acid; 0/Retinoids; 302-79-4/Tretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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