Document Detail

The results of a simplified technique for safe carotid stenting in the elderly.
MedLine Citation:
PMID:  21890307     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of this study was to report the preliminary experience of a modified transcervical carotid angioplasty and stenting (CAS) technique with filter protection and flow reversal only during filter placement in patients unsuitable for transfemoral CAS and at high risk for carotid endarterectomy (CEA).
PATIENTS AND METHODS: Twenty-five of 132 patients, aged 75 to 86 years old, with severe carotid stenosis had been selected. Eighteen patients had transient ischemic attacks (TIAs) in the last month and seven patients were asymptomatic. Patients with limited life expectancy were not included. The common carotid artery (CCA) was mobilized and cannulated. The flow in the internal carotid artery (ICA) was reversed by occluding the proximal CCA and connecting the introducing sheath to a blood transfusion bag positioned close to the floor, instead of returning it directly to the venous system. This produced retrograde flow in the ICA in all patients as a result of greater pressure gradient. The carotid filter was inserted to the distal ICA under retrograde flow and then antegrade flow was resumed and CAS was performed. All patients were autotransfused except for four patients who had severe renal insufficiency to avoid readministration of contrast media.
RESULTS: All procedures were successful except in one patient converted to open endarterectomy because of CCA dissection (technical success rate 97.5%) and one patient who had a TIA involving the right hand 10 hours after CAS and recovered completely after 3 hours (event rate 2.5%). Reversed flow was visualized with intraoperative angiography in the ICA in all patients. Twenty-two patients were discharged the next morning and three (12%) on the following day because of hypotension. The duration of reversed flow was 1 to 4 minutes (mean, 1.5 minutes), the amount of blood collected was 100 to 400 mL (mean, 250 mL), and none of these patients had any hemodynamic disturbance during the procedure. Creatinine levels showed no increase postoperatively in either patient. The patients were followed-up clinically and with color Duplex scan for 3 to 24 months, so far, and they are free of symptoms or significant restenosis.
CONCLUSION: The results of this preliminary study indicate that the transcervical approach with flow reversal during the insertion of the protecting filter allows CAS with minimal interruption of cerebral circulation and is simple and safe in patients unsuitable for CEA and transfemoral CAS for anatomic reasons. Further research with randomization and with pre-procedure and post-procedure diffusion-weighted magnetic resonance imaging (DW-MRI) is required in order to expand the indications of this method.
Dimitrios Christopoulos; Eugenios Philippov
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Publication Detail:
Type:  Journal Article     Date:  2011-09-03
Journal Detail:
Title:  Journal of vascular surgery     Volume:  54     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-05     Completed Date:  2012-04-03     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1637-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.
Department of Vascular Surgery, B'Surgical Unit, Genimmatas General Hospital, University of Thessaloniki Medical School, Thessaloniki, Greece.
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MeSH Terms
Age Factors
Aged, 80 and over
Angioplasty / methods*
Carotid Artery, Internal*
Carotid Stenosis / therapy*
Cohort Studies
Feasibility Studies
Patient Selection
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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