Document Detail


The results of in vitro fertilization-embryo transfer in couples with unexplained infertility failing to conceive with superovulation and intrauterine insemination.
MedLine Citation:
PMID:  7789586     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the results of IVF-ET in couples with long-standing unexplained infertility who had failed to conceive with four to six cycles of superovulation and IUI. DESIGN: Retrospective case control series. SETTING: University IVF-ET center. PATIENTS: One hundred seventeen couples with unexplained infertility who had failed to conceive with superovulation and IUI underwent 157 cycles of IVF-ET. Results were compared with 194 tubal factor couples subjected to 250 IVF-ET cycles within the same time period. RESULTS: Total fertilization failure events were more common (20.4% versus 7.6%) and tended to be repetitive in couples with unexplained infertility. When total fertilization failure events were excluded, fertilization rates (57.8% versus 60.9%) and cumulative clinical pregnancy rates over three cycles (55.4% versus 46.5%) were similar in unexplained infertility and tubal disease groups. CONCLUSIONS: Couples with unexplained infertility failing to conceive with superovulation and IUI have a favorable outcome when treated subsequently with IVF-ET. Conception rates similar to couples with tubal disease may be expected despite a higher incidence of total fertilization failure events.
Authors:
T Gürgan; B Urman; H Yarali; H A Kişnişçi
Related Documents :
607806 - Pelvic endometriosis: infertility and pelvic pain.
10342846 - Transgenic mice with chronically elevated luteinizing hormone are infertile due to anov...
14520186 - Optimizing use of assisted reproduction.
7282306 - Uterine anomalies in diethylstilbestrol-exposed women with fertility disorders.
20226996 - Gestational nutrition improves outcomes of vaginal deliveries in jordan: an epidemiolog...
20956896 - Doppler prediction of perinatal outcome in pregnancy induced hypertension and intrauter...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  64     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-07-25     Completed Date:  1995-07-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  93-7     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Hacettepe, Ankara, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Embryo Transfer*
Fallopian Tubes
Female
Fertilization in Vitro*
Humans
Infertility / therapy*
Infertility, Female / therapy
Insemination, Artificial, Homologous
Male
Pregnancy*
Retrospective Studies
Superovulation
Treatment Failure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cumulative number and morphological score of embryos resulting in success: realistic expectations fr...
Next Document:  The pregnancy rates of cohorts of idiopathic infertility couples gives insights into the underlying ...