| The results of in vitro fertilization-embryo transfer in couples with unexplained infertility failing to conceive with superovulation and intrauterine insemination. | |
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MedLine Citation:
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PMID: 7789586 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine the results of IVF-ET in couples with long-standing unexplained infertility who had failed to conceive with four to six cycles of superovulation and IUI. DESIGN: Retrospective case control series. SETTING: University IVF-ET center. PATIENTS: One hundred seventeen couples with unexplained infertility who had failed to conceive with superovulation and IUI underwent 157 cycles of IVF-ET. Results were compared with 194 tubal factor couples subjected to 250 IVF-ET cycles within the same time period. RESULTS: Total fertilization failure events were more common (20.4% versus 7.6%) and tended to be repetitive in couples with unexplained infertility. When total fertilization failure events were excluded, fertilization rates (57.8% versus 60.9%) and cumulative clinical pregnancy rates over three cycles (55.4% versus 46.5%) were similar in unexplained infertility and tubal disease groups. CONCLUSIONS: Couples with unexplained infertility failing to conceive with superovulation and IUI have a favorable outcome when treated subsequently with IVF-ET. Conception rates similar to couples with tubal disease may be expected despite a higher incidence of total fertilization failure events. |
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Authors:
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T Gürgan; B Urman; H Yarali; H A Kişnişçi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 64 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1995 Jul |
Date Detail:
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Created Date: 1995-07-25 Completed Date: 1995-07-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 93-7 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Hacettepe, Ankara, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Embryo Transfer* Fallopian Tubes Female Fertilization in Vitro* Humans Infertility / therapy* Infertility, Female / therapy Insemination, Artificial, Homologous Male Pregnancy* Retrospective Studies Superovulation Treatment Failure |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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