Document Detail

The responsiveness of generic quality of life instruments in rheumatic diseases. A systematic review of randomized controlled trials.
MedLine Citation:
PMID:  9918266     Owner:  NLM     Status:  MEDLINE    
To review the available evidence that has used generic instruments alone or in comparison with disease specific instruments. A systematic review was carried out using the methods recommended by the Cochrane Collaboration. We used MEDLINE and EMBASE searches and we performed a hand search of the abstracts listed under "quality of life" at American College of Rheumatology (ACR) meetings. Selection was limited to randomized controlled trials (RCT) using generic instruments in populations older than 18 years with any of the following diseases: rheumatoid arthritis, fibromyalgia, osteoporosis, osteoarthritis, systemic lupus erythematosus, and ankylosing spondylitis. Language was restricted to English papers. Studies using only disease-specific instruments were excluded. From 488 articles retrieved, 13 reports of 10 randomized controlled trials were selected. There were 101 abstracts on quality of life in ACR abstract books; 78 abstracts contained data on generic instruments, and of these, 9 described their use in RCT. Despite a substantial increase in the number of papers and abstracts addressing different aspects of generic questionnaires, the majority of the papers were descriptive. The evidence is not yet available to document that any of the generic instruments pass the requirements of the OMERACT Filter.
Z Ortiz; B Shea; M Garcia Dieguez; M Boers; P Tugwell; A Boonen; G Wells
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  26     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-03-23     Completed Date:  1999-03-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  210-6     Citation Subset:  IM    
Academia Nacional de Medicina de Buenos Aires, Argentina.
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MeSH Terms
Outcome Assessment (Health Care)*
Quality of Life*
Randomized Controlled Trials as Topic*
Rheumatic Diseases* / drug therapy

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