Document Detail


The response of blood flow between the internal thoracic and ileocecal arteries to inotropic agents in a canine model.
MedLine Citation:
PMID:  9505320     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The pharmacologic response of coronary artery bypass conduits is of great importance. This study was designed to clarify the response of blood flow between the internal thoracic artery (ITA) and the ileocecal artery (ICA) to inotropic agents. The responses of the ITA and ICA to epinephrine, dopamine, isoproterenol, and dobutamine were examined by collecting free-flowing blood from a canine model. There were no significant differences in the response to inotropic agents between the ITA and the ICA. Epinephrine and dopamine increased the graft flow, whereas isoproterenol and dobutamine decreased the graft flow percentages of the cardiac output. These results suggest that the flow response to inotropic agents is equivalent in canine ITA and ICA grafts.
Authors:
Y Tada; H Tsuboi; K Suzuki; T Katoh; N Zempo; Y Fujimura; K Esato
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery today     Volume:  28     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1998  
Date Detail:
Created Date:  1998-05-08     Completed Date:  1998-05-08     Revised Date:  2006-08-03    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  70-5     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Yamaguchi University School of Medicine, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cardiotonic Agents / pharmacology*
Cecum / blood supply
Coronary Artery Bypass* / methods
Coronary Circulation / drug effects*
Dobutamine / pharmacology
Dogs
Dopamine / pharmacology
Epinephrine / pharmacology
Ileum / blood supply
Internal Mammary-Coronary Artery Anastomosis
Isoproterenol / pharmacology
Regional Blood Flow / drug effects
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; 34368-04-2/Dobutamine; 51-43-4/Epinephrine; 7683-59-2/Isoproterenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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