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The respiratory tract and the environment.
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MedLine Citation:
PMID:  598343     Owner:  NLM     Status:  MEDLINE    
The primary determinants of pulmonary disease are environmental. The same thinness and delicacy of the air-blood barrier which allows rapid exchange of oxygen and carbon dioxide also reduce its effectiveness as a barrier to inhaled allergens, carcinogens, toxic particles, and noxious gases, and micro-organisms. Adults breath 10,000 to 20,000 liters of air daily. This volume of air contains potentially hazardous contaminating particles and gases. Future research should explore the diverse physiological mechanisms which prevent the accumulation and deleterious action of inhaled particles and gases. Since most pulmonary diseases are either initiated by or at least aggravated by the inhalagion of particles and gases, the role of environmental factors in the development of respiratory disease is an area worthy of continued support.
J D Brain
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Environmental health perspectives     Volume:  20     ISSN:  0091-6765     ISO Abbreviation:  Environ. Health Perspect.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1978-03-10     Completed Date:  1978-03-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0330411     Medline TA:  Environ Health Perspect     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  113-26     Citation Subset:  IM    
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MeSH Terms
Environmental Health
Environmental Pollutants / adverse effects*
Lung Diseases / chemically induced*,  diagnosis
Macrophages / physiology
Respiratory Function Tests
Respiratory Physiological Phenomena*
Respiratory System / anatomy & histology
Reg. No./Substance:
0/Dust; 0/Environmental Pollutants; 0/Gases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): Environ Health Perspect
ISSN: 0091-6765
Article Information
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Print publication date: Month: 10 Year: 1977
Volume: 20First Page: 113 Last Page: 126
ID: 1637344
PubMed Id: 598343

The respiratory tract and the environment.
J D Brain

Article Categories:
  • Research Article

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