| Is respiratory failure a consequence of blood transfusion? | |
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MedLine Citation:
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PMID: 7401203 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The pulmonary entrapment of microaggregates, platelets, and white cells in stored blood is thought to contribute to abnormalities in lung function. Washing of red cells removes these potentially damaging elements. This prospective, randomized, double-blind study compares the pulmonary function of patients undergoing abdominal aortic aneurysmectomy who received either washed or unwashed red cell concentrates. Both groups received equivalent volumes of blood, albumin, and balanced salt solution duing surgery. Postoperatively, no differences were observed in the physiologic shunt, QS/QT, pulmonary artery pressure, pulmonary vascular resistance, or effective dynamic compliance. The cardiac index at equivalent left ventricular filling pressures was the same. The results indicate that it is unlikely that microaggregates or other formed elements in stored blood lead to compromised pulmonary function. |
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Authors:
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G A Grindlinger; A M Vegas; W H Churchill; C R Valeri; H B Hechtman |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of trauma Volume: 20 ISSN: 0022-5282 ISO Abbreviation: J Trauma Publication Date: 1980 Aug |
Date Detail:
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Created Date: 1980-10-27 Completed Date: 1980-10-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376373 Medline TA: J Trauma Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 627-31 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aortic Aneurysm / physiopathology, surgery Blood Gas Analysis Blood Transfusion / adverse effects* Cell Aggregation Double-Blind Method Erythrocyte Transfusion Female Hemodynamics Humans Male Prospective Studies Random Allocation Respiratory Function Tests Respiratory Insufficiency / etiology* |
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