| The reservoir of Plasmodium falciparum malaria in a holoendemic area of western Kenya. | |
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MedLine Citation:
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PMID: 1359683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The reservoir of infectious Plasmodium falciparum gametocytes in a population living in an area of holoendemic malaria in western Kenya was estimated by directly feeding mosquitoes on volunteers. Resulting mosquito infections were assessed both by midgut examination for oocysts and by enzyme-linked immunosorbent assay for P. falciparum circumsporozoite antigen. Calculations based on the age structure of the population and the resulting rates of mosquito infections indicated that children under 10 years of age were responsible for 72% of mosquito infections, individuals between 10 and 21 years of age contributed 12%, and those over 21 years of age accounted for 16%. No infection resulted in mosquitoes fed on infants less than 1 year of age. |
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Authors:
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A K Githeko; A D Brandling-Bennett; M Beier; F Atieli; M Owaga; F H Collins |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Transactions of the Royal Society of Tropical Medicine and Hygiene Volume: 86 ISSN: 0035-9203 ISO Abbreviation: Trans. R. Soc. Trop. Med. Hyg. Publication Date: 1992 Jul-Aug |
Date Detail:
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Created Date: 1992-12-09 Completed Date: 1992-12-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7506129 Medline TA: Trans R Soc Trop Med Hyg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 355-8 Citation Subset: IM |
Affiliation:
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Kenya Medical Research Institute, Vector Biology and Control Research Centre, Kisumu. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Culicidae / parasitology Disease Reservoirs* Humans Kenya / epidemiology Malaria, Falciparum / epidemiology*, parasitology, transmission Plasmodium falciparum / isolation & purification Prevalence Protozoan Infections / epidemiology, parasitology |
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