| A report of two cases of Kawasaki disease treated with plasma exchange. | |
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MedLine Citation:
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PMID: 18387169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Kawasaki disease is a generalized vasculitis of unknown etiology that occurs predominantly in infants and young children. It is very important to prevent its cardiovascular manifestations, especially coronary artery lesions. Early treatment with intravenous immunoglobulin reduces cardiovascular sequelae, but some patients do not respond to this treatment, and they have a high incidence of coronary artery lesions. On the other hand, acute heart failure is rare in Kawasaki disease. We report on the cases of two patients with persistent fever and shock even after intravenous immunoglobulin therapy. In both cases, plasma exchange may have reduced the risk of coronary artery lesions and proved effective against acute heart failure with catecholamine-refractory shock; yet the mechanism of this improvement remains unclear. |
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Authors:
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Tomonori Harada; Shuichi Ito; Kentaro Shiga; Aya Inaba; Hiroyuki Machida; Yukoh Aihara; Shumpei Yokota |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Volume: 12 ISSN: 1744-9987 ISO Abbreviation: Ther Apher Dial Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-04 Completed Date: 2008-05-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101181252 Medline TA: Ther Apher Dial Country: Australia |
Other Details:
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Languages: eng Pagination: 176-9 Citation Subset: IM |
Affiliation:
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Children's Medical Center, Yokohama City University Medical Center, Yokohama, Japan. haradat@mbd.ocn.ne.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Coronary Vessels / pathology Female Heart Failure / etiology, prevention & control* Humans Immunoglobulins, Intravenous / therapeutic use Male Mucocutaneous Lymph Node Syndrome / complications, physiopathology, therapy* Plasma Exchange* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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