Document Detail


A replacement-first approach to toxicity testing is necessary to successfully reauthorize TSCA.
MedLine Citation:
PMID:  22130480     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The Toxic Substances Control Act is the principal US law governing industrial chemicals. Over the past three and one half decades, it has become clear that a considerable toxicological information gap exists about chemicals in commerce. The current provisions of the US TSCA law have failed to fill, and perhaps even exacerbated, that gap. For at least the past 5 years, bills have been introduced before the US Congress to reauthorize TSCA.Filling the toxicological information gap has been one of the driving forces for this call for substantial change. This article describes efforts to modernize TSCA, with an emphasis on the new provisions that would be put into place if the legislation became law. The article shows that only by implementing a "replacement-first" strategy - a strategy that is not currently incorporated into TSCA reauthorization efforts - can TSCA modernization efforts potentially fill the toxic data voids.
Authors:
Paul A Locke; D Bruce Myers
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ALTEX     Volume:  28     ISSN:  1868-596X     ISO Abbreviation:  ALTEX     Publication Date:  2011  
Date Detail:
Created Date:  2011-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100953980     Medline TA:  ALTEX     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  266-72     Citation Subset:  IM    
Affiliation:
Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Center for Alternatives to Animal testing, Baltimore, MD, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Plasma adiponectin elevation in elderly individuals with subsyndromal depression.
Next Document:  How are reproductive toxicity and developmental toxicity addressed in REACH dossiers?