Document Detail


The renin-angiotensin system and aldosterone in hypertension: a brief review of some aspects.
MedLine Citation:
PMID:  7016779     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The biochemistry of the renin-angiotensin system has been outlined. The relationship between plasma angiotension II levels, basal or raised as a result of infusion, and blood pressure and aldosterone has been explored in normal human subjects and animals, showing how these relationships can be modified by changes in sodium status and duration of exposure to high circulating levels of the octapeptide. Finally, the relationship has been examined in different categories of hypertensive disease, such as essential hypertension.
Authors:
R Fraser; J J Brown; A F Lever; J J Morton; J I Robertson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of obesity     Volume:  5 suppl 1     ISSN:  0307-0565     ISO Abbreviation:  Int J Obes     Publication Date:  1981  
Date Detail:
Created Date:  1981-08-20     Completed Date:  1981-08-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7703240     Medline TA:  Int J Obes     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  115-23     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aldosterone / physiology*
Angiotensin II / physiology*
Blood Pressure
Humans
Hyperaldosteronism / physiopathology
Hypertension / physiopathology*
Renin / physiology*
Chemical
Reg. No./Substance:
11128-99-7/Angiotensin II; 52-39-1/Aldosterone; EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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