Document Detail

The renal renin-angiotensin system.
MedLine Citation:
PMID:  19948673     Owner:  NLM     Status:  In-Process    
The renin-angiotensin system (RAS) is a critical regulator of sodium balance, extracellular fluid volume, vascular resistance, and, ultimately, arterial blood pressure. In the kidney, angiotensin II exerts its effects to conserve salt and water through a combination of the hemodynamic control of renal blood flow and glomerular filtration rate and tubular epithelial cell sodium chloride and water transport mechanisms. Pharmacological inhibition of the actions of the RAS are widely used in the treatment of patients with hypertension, congestive heart failure, left ventricular dysfunction, pulmonary and systemic edema, diabetic nephropathy, cirrhosis of the liver, scleroderma, and migraines. Therefore, a thorough understanding of the influences of the RAS on normal renal physiology is of major importance for first-year medical students.
Lisa M Harrison-Bernard
Related Documents :
9504863 - The tsukuba hypertensive mouse (transgenic mouse carrying human genes for both renin an...
6791173 - Endocrine mechanisms in the pathogenesis of essential hypertension. iii. special refere...
7013723 - Comparative evaluation of the factors regulating vascular resistance in dogs, anestheti...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in physiology education     Volume:  33     ISSN:  1522-1229     ISO Abbreviation:  Adv Physiol Educ     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100913944     Medline TA:  Adv Physiol Educ     Country:  United States    
Other Details:
Languages:  eng     Pagination:  270-4     Citation Subset:  IM    
Department of Physiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Ethical approval for research in physiology education.
Next Document:  The kidney and acid-base regulation.