Document Detail


The remarkable cochlear amplifier.
MedLine Citation:
PMID:  20541061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This composite article is intended to give the experts in the field of cochlear mechanics an opportunity to voice their personal opinion on the one mechanism they believe dominates cochlear amplification in mammals. A collection of these ideas are presented here for the auditory community and others interested in the cochlear amplifier. Each expert has given their own personal view on the topic and at the end of their commentary they have suggested several experiments that would be required for the decisive mechanism underlying the cochlear amplifier. These experiments are presently lacking but if successfully performed would have an enormous impact on our understanding of the cochlear amplifier.
Authors:
J Ashmore; P Avan; W E Brownell; P Dallos; K Dierkes; R Fettiplace; K Grosh; C M Hackney; A J Hudspeth; F Jülicher; B Lindner; P Martin; J Meaud; C Petit; J Santos-Sacchi; J R Santos Sacchi; B Canlon
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Hearing research     Volume:  266     ISSN:  1878-5891     ISO Abbreviation:  Hear. Res.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-27     Revised Date:  2011-10-28    
Medline Journal Info:
Nlm Unique ID:  7900445     Medline TA:  Hear Res     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-17     Citation Subset:  IM    
Affiliation:
Department of Neuroscience, Physiology and Pharmacology and UCL Ear Institute, Gower Street, London WC1E 6BT, UK. j.ashmore@ucl.ac.uk <j.ashmore@ucl.ac.uk>
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MeSH Terms
Descriptor/Qualifier:
Animals
Auditory Perception
Cell Movement
Cochlea / physiology*
Feedback, Physiological
Hair Cells, Auditory / physiology
Hearing*
Humans
Ion Transport
Mechanotransduction, Cellular*
Membrane Potentials
Models, Biological
Pressure
Sound
Vibration
Grant Support
ID/Acronym/Agency:
DC000354/DC/NIDCD NIH HHS; DC00089-38/DC/NIDCD NIH HHS; DC008130/DC/NIDCD NIH HHS; DC009913/DC/NIDCD NIH HHS; NIDCD DC00273//PHS HHS; NIH-NIDCD R01-04084//PHS HHS; NIH-NIDCD RO1 DC01362//PHS HHS; R01-DC002775/DC/NIDCD NIH HHS
Comments/Corrections
Erratum In:
Hear Res. 2011 Oct;280(1-2):245
Note: Sacchi, J R Santos [corrected to Santos-Sacchi, J]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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