Document Detail


A reliable, non-invasive measurement tool for anisotropy in normal skin and scar tissue.
MedLine Citation:
PMID:  20637002     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Anisotropy of the skin varies depending on different locations and pathological conditions. Currently, no reliable non-invasive measurement tool is available for tissue anisotropy. The Reviscometer is an anisotropy measurement tool that measures the resonance running time (RRT) of a shock wave. This study was initiated to establish the reliability of the Reviscometer on normal skin and scars, and to provide basic information on tissue alignment in normal skin and scars. METHODS: Fifty volunteers and 50 patients underwent measurements on normal skin and scars, respectively. All measurements were performed by the same two observers. Measurements on normal skin were performed on the forearm, upper arm, and abdomen. RESULTS: The results showed that the intraclass correlation coefficient of the inter-observer reliability was > or =0.79 on normal skin and > or =0.86 on scars. In normal skin, the highest mean RRT was found on the abdomen (156.4+/-48.8), followed by the upper arm (123.2+/-33.6) and the forearm (112.5+/-24.3). A significantly lower mean RRT was found in scars (52.3+/-21.9) compared with normal skin (91.6+/-37.7). CONCLUSION: Reviscometer measurements were reliable for normal skin and scars. In addition, clear differences between scars and normal skin but also within different locations on normal skin were identified. The Reviscometer can be considered for the evaluation of the efficacy of different treatments.
Authors:
Pauline D H M Verhaegen; Evelien M Res; Arna van Engelen; Esther Middelkoop; Paul P M van Zuijlen
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies    
Journal Detail:
Title:  Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)     Volume:  16     ISSN:  1600-0846     ISO Abbreviation:  Skin Res Technol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9504453     Medline TA:  Skin Res Technol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  325-31     Citation Subset:  IM    
Affiliation:
Association of Dutch Burn Centres, Beverwijk, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anisotropy
Cicatrix / pathology*
Dermatology / instrumentation*,  standards*,  statistics & numerical data
Female
Humans
Male
Middle Aged
Observer Variation
Reference Values
Reproducibility of Results
Skin / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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