| The reliability of continuous measurement of mixed venous oxygen saturation during exercise in patients with chronic heart failure. | |
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MedLine Citation:
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PMID: 17957380 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous assessment of mixed venous oxygen saturation (cSvO(2)) during exercise using a fiber optic pulmonary artery catheter can provide valuable information on the physiological determinants of the exercise capacity in patients with chronic heart failure (CHF). Since its accuracy is not well established during exercise, this study evaluated the reliability of a fiber optic pulmonary artery catheter for measuring SvO(2 )during exercise in CHF patients. Ten patients with stable CHF performed steady-state exercise tests at 30 and 80% of the ventilatory threshold and consequently a symptom-limited incremental exercise test. During the tests, SvO(2 )was monitored continuously using a fiber optic pulmonary artery catheter (CCOmbo, Edwards Lifesciences, Irvine, CA, USA) and by oximetric analysis of mixed venous blood samples obtained at rest (n = 26), steady state (n = 17) and peak exercise (n = 8). There was a significant correlation between oximetrically determined SvO(2) and cSvO(2) values (r = 0.97). The bias between both methods was 0.6% with limits of agreement from -8 to 9%. The limits of agreement for SvO(2 )values <30% (n = 16) were slightly wider than for SvO(2) values >30% (n = 35) (from -10 to 12% and from -7 to 8%, respectively). In conclusion, continuous measurement of SvO(2 )during exercise using a fiber optic pulmonary catheter is reliable in patients with CHF, with somewhat less accurate measurements of SvO(2 )below 30%. |
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Authors:
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Boudewijn T H M Sleutjes; Hareld M C Kemps; Eric J M Thijssen; Frans N van de Vosse; Goof Schep; Chris H Peters; Pieter F F Wijn |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Validation Studies Date: 2007-10-24 |
Journal Detail:
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Title: European journal of applied physiology Volume: 102 ISSN: 1439-6319 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-03-14 Completed Date: 2008-06-18 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: Germany |
Other Details:
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Languages: eng Pagination: 493-6 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering, Eindhoven University of Technology, Postbox 513, 5600 MB, Eindhoven, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Catheterization, Swan-Ganz / instrumentation, standards* Fiber Optic Technology Heart Failure / physiopathology* Humans Male Middle Aged Monitoring, Physiologic / instrumentation, standards* Optical Fibers Oxygen Consumption / physiology* Physical Exertion / physiology* Pulmonary Artery / physiology Reproducibility of Results Veins / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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