Document Detail


The relevance of symmetric and asymmetric cell divisions to human central nervous system diseases.
MedLine Citation:
PMID:  21288724     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
During development of the embryonic central nervous system (CNS), large numbers of neurons and glia are generated from the neuroepithelium and its progenitor derivatives as a result of symmetric and asymmetric cell divisions. We describe the biology of symmetric and asymmetric cell divisions in the CNS as gleaned from animal models, and discuss the relevance of these processes to human CNS development and disease.
Authors:
Kol Jia Yong; Benedict Yan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-31
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  -     ISSN:  1532-2653     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-2-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Cancer Science Institute, National University of Singapore, Singapore; Department of Pathology, National University Hospital and Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore, Singapore.
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