| The relevance of hypertension and oedema in pregnancy. | |
| | |
MedLine Citation:
|
PMID: 7428567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The triad of severe pre-eclampsia is often described as a combination of hypertension, oedema and proteinuria. Hypertension alone arising in the second half of pregnancy however is not associated with any greater perinatal mortality or low birthweight than normotensive primigravidae and it is probable that this hypertension may be either physiological or a manifestation of essential hypertension or, in some cases, a mild form of pre-eclampsia. Oedema also does not necessarily signify abnormality. High weight gain, fluid retention or oedema is associated with a lower incidence of small babies, but with a higher incidence of pre-eclampsia. Considerable amounts of water retention can occur in normal pregnancy, either measured as an increase during pregnancy, or as a fall after delivery. The diuretics cyclopenthiazide, spironolactone and clopamide given prophylactically to high weight gain primigravidae did not prevent the onset of proteinuric pre-eclampsia, but caused the babies to be lighter in weight than those of controls. Sodium potassium and water content of leucocytes from primigravidae with proteinuric pre-eclampsia is the same as in mild pre-eclampsia and normal pregnancy. Although salt and water retention are common features of pre-eclampsia, they do not cause the condition and are not an essential part of it. |
| | |
Authors:
|
I MacGillivray; D M Campbell |
Related Documents
:
|
6112487 - Decrease prostacyclin production: a characteristic of chronic placental insufficiency s... 9013097 - Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancie... 17826887 - The transient increase of oxidative stress during normal pregnancy is higher and persis... 19986787 - The prognosis and treatment of eclampsia and albuminuria, with special reference to the... 10722627 - Effects of shiga toxin 2 on lethality, fetuses, delivery, and puerperal behavior in pre... 20595947 - The impact of uterine leiomyomas on reproductive outcomes. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical and experimental hypertension Volume: 2 ISSN: 0148-3927 ISO Abbreviation: Clin Exp Hypertens Publication Date: 1980 |
Date Detail:
|
Created Date: 1981-01-26 Completed Date: 1981-01-26 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7803060 Medline TA: Clin Exp Hypertens Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 897-914 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Birth Weight
/
drug effects Body Weight Diuretics / therapeutic use Edema / complications* Female Humans Hypertension / complications* Leukocytes / analysis Potassium / metabolism Pre-Eclampsia / diagnosis*, drug therapy Pregnancy Pregnancy Complications, Cardiovascular* / drug therapy Proteinuria / complications Sodium / metabolism Tissue Distribution Water-Electrolyte Balance |
| Chemical | |
Reg. No./Substance:
|
0/Diuretics; 7440-09-7/Potassium; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moder...
Next Document: Blood pressure response in hypertensive pregnancies treated with cortisol.