Document Detail

On the relative content of G,C bases in codons of amino acids corresponding to class I and II aminoacyl-tRNA synthetases.
MedLine Citation:
PMID:  11434105     Owner:  NLM     Status:  MEDLINE    
We have analyzed the relative G,C content from protein coding regions of 530 organisms and found that the ratio of the G,C content of the codons of the amino acids corresponding to Class II and Class I aminoacyl-tRNA synthetases decreases in a statistically significant way from prokaryotes to animals. This can be interpreted assuming that an initial asymmetry between the G,C content of codons of Class I and II amino acids existed and has decreased in the course of evolution.
A R Cavalcanti; R Ferreira
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life     Volume:  31     ISSN:  0169-6149     ISO Abbreviation:  Orig Life Evol Biosph     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-07-03     Completed Date:  2001-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8610391     Medline TA:  Orig Life Evol Biosph     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  257-69     Citation Subset:  IM; S    
Department of Ecology and Evolution, University of Chicago, 1101 East 57th Street, 60637, Chicago, IL, USA.
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MeSH Terms
Amino Acids / genetics
Amino Acyl-tRNA Synthetases / classification*,  genetics*
Archaea / enzymology,  genetics
Bacteria / enzymology,  genetics
Base Composition
Eukaryotic Cells / enzymology
Evolution, Molecular*
Monte Carlo Method
Vertebrates / genetics
Reg. No./Substance:
0/Amino Acids; 0/Codon; EC 6.1.1.-/Amino Acyl-tRNA Synthetases

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