Document Detail

The relationship of transverse sinus stenosis to bony groove dimensions provides an insight into the aetiology of idiopathic intracranial hypertension.
MedLine Citation:
PMID:  18622602     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Transverse sinus tapered narrowings are frequently identified in patients with idiopathic intracranial hypertension (IIH); however, it remains unclear whether they are primary stenoses or whether they occur secondary to raised cerebrospinal fluid pressure. Computed tomographic venography demonstrates both the morphology of the venous system and the adjacent bony grooves so it may provide an insight into the aetiology of these transverse sinus stenoses. MATERIALS AND METHODS: Tapered transverse sinus narrowings (>50%) were studied in 19 patients without IIH and 14 patients with IIH. Computed tomography vascular studies were reviewed and the dimensions of the venous sinuses and bony grooves at the sites of maximum and minimum transverse sinus area dimensions were recorded. RESULTS: There was demonstrated to be a strong correlation of bony groove height with venous sinus height at the largest portions of the transverse sinus in both IIH patients and non-IIH subjects as well as at the transverse sinus narrowing in non-IIH subjects. There was a discordant relationship between bony groove height and venous sinus height at the site of transverse sinus stenoses in IIH patients. In 5/23 IIH transverse sinus stenoses, the bony groove height was proportionate to that seen in non-IIH subjects. There were a further 8/23 cases where the small or absent sinus was associated with an absent bony groove. CONCLUSION: Transverse sinus tapered narrowings in subjects without IIH and in the majority of patients with IIH were associated with proportionately small or absent grooves, and these are postulated to be primary or fixed. Some patients with IIH demonstrate tapered transverse sinus stenoses with disproportionately large bony grooves, suggesting a secondary or acquired narrowing. This implies a varied aetiology for the transverse sinus stenoses of IIH.
S E J Connor; M A Siddiqui; V R Stewart; E A M O'Flynn
Publication Detail:
Type:  Journal Article     Date:  2008-07-12
Journal Detail:
Title:  Neuroradiology     Volume:  50     ISSN:  1432-1920     ISO Abbreviation:  Neuroradiology     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-21     Completed Date:  2009-05-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  999-1004     Citation Subset:  IM    
Neuroradiology Department, Ruskin Wing, King's College Hospital, Denmark Hill, London, UK.
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MeSH Terms
Case-Control Studies
Cohort Studies
Constriction, Pathologic / complications,  physiopathology,  radiography
Middle Aged
Occipital Bone / pathology*,  radiography
Pseudotumor Cerebri / etiology*,  pathology,  radiography*
Risk Factors
Tomography, X-Ray Computed
Transverse Sinuses / pathology*,  radiography
Young Adult

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