Document Detail

The relationship of myocarditis to dilated cardiomyopathy.
MedLine Citation:
PMID:  6100098     Owner:  NLM     Status:  MEDLINE    
Three patients with congestive cardiomyopathy are reported in whom high neutralizing antibody titres to Coxsackie B viruses were detected. At post-mortem examination, all three had histologically demonstrable chronic inflammation of the myocardium. The hearts of ten patients dying in cardiac failure due to other causes showed no comparable inflammatory infiltration. This provides further evidence that Coxsackie B viral myocarditis is involved in the pathogenesis of some cases of dilated cardiomyopathy. One patient also had pulmonary veno-occlusive disease. This has been reported in association with myocarditis once previously in an infant. A viral aetiology has been postulated. It seems likely in this patient to have also been due to a Coxsackie B virus.
C G MacArthur; D Tarin; J F Goodwin; K A Hallidie-Smith
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European heart journal     Volume:  5     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-06-26     Completed Date:  1985-06-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1023-35     Citation Subset:  IM    
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MeSH Terms
Antibodies, Viral / analysis
Cardiomegaly / etiology*,  pathology
Coxsackievirus Infections / complications*
Enterovirus B, Human / immunology
Heart Failure / etiology*,  pathology
Middle Aged
Myocarditis / complications*
Pulmonary Veins / pathology
Reg. No./Substance:
0/Antibodies, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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