| The relationship of left atrial volume and left atrial pressure in patients with hypertrophic cardiomyopathy: an echocardiographic and cardiac catheterization study. | |
| | |
MedLine Citation:
|
PMID: 19524402 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Left atrial enlargement is a marker of diastolic dysfunction, which is present in most patients with hypertrophic cardiomyopathy (HCM). It is unclear as to whether left atrial volume is a reliable measure of ventricular filling pressures in these patients. METHODS: Left atrial volume index (LAVI) was measured in 100 symptomatic patients with HCM using transthoracic echocardiography, followed by cardiac catheterization with transseptal measurement of left atrial pressure (LAP) and end-diastolic pressure within 48 hours. RESULTS: LAVI was only modestly related to mean LAP (r=0.24, P=.02), and there was no significant relation to end-diastolic pressure (r=0.11, P=.28). The specificity of increased LAVI (>28 cm3/m2) for elevated LAP (>15 mm Hg) was poor (16%). However, all patients with normal LAVI had normal LAP. CONCLUSIONS: Although left atrial size may reflect chronic changes due to diastolic dysfunction in HCM, the relation of increased LAVI to ventricular filling pressures is modest. Nonetheless, a normal LAVI suggests normal ventricular filling pressures in patients with HCM. |
| | |
Authors:
|
Jeffrey B Geske; Paul Sorajja; Rick A Nishimura; Steve R Ommen |
Publication Detail:
|
Type: Journal Article Date: 2009-06-12 |
Journal Detail:
|
Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 22 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2009 Aug |
Date Detail:
|
Created Date: 2009-08-03 Completed Date: 2009-10-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
|
Languages: eng Pagination: 961-6 Citation Subset: IM |
Affiliation:
|
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Pressure* Cardiomyopathy, Hypertrophic / physiopathology*, ultrasonography* Echocardiography / methods* Female Heart Atria / physiopathology*, ultrasonography* Heart Catheterization / methods* Humans Male Middle Aged Organ Size |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Left ventricular diastolic filling pressures during dobutamine stress echocardiography: relationship...
Next Document: Reconstruction of volumetric ultrasound panorama based on improved 3D SIFT.