| The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. | |
| | |
MedLine Citation:
|
PMID: 21700429 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The ketogenic diet (KD) is a treatment of infantile spasms (IS). Here, we examine the efficacy of KD in medically refractory IS, examine its impact on growth in infants, and explore its mechanism of action. At 1-3 months after the initiation of the KD, 46% of twenty-six patients had a greater than 90% reduction in IS. No significant relationships between reduction in IS and serum β-hydroxybutyrate, or glucose levels were identified. Also, the KD had not significantly altered patient's growth parameters. Thus, in corroborating with prior studies, we demonstrate the KD is a well-tolerated and efficacious treatment of IS. |
| | |
Authors:
|
Adam L Numis; Margaret B Yellen; Catherine J Chu-Shore; Heidi H Pfeifer; Elizabeth A Thiele |
Related Documents
:
|
22080499 - Growth hormone and igf-1 deficiency exacerbate high-fat diet-induced endothelial impair... 10963729 - Effect of vitamin e supplementation on antibody levels against malondialdehyde modified... 7643239 - Ldl receptor activity is down-regulated similarly by a cholesterol-containing diet high... 19748619 - Contribution of apolipoprotein e genotype and docosahexaenoic acid to the ldl-cholester... 15242239 - A new approach to the quantitative measurement of dense ldl subfractions. 10717489 - Effect of menopause on low-density lipoprotein oxidation: is oestrogen an important det... 8774219 - Crude protein and supplemental dietary tryptophan effects on growth and tissue neurotra... 8487489 - Controlled diet in phenylketonuria may cause serum carnitine deficiency. 20842439 - Novel snps in the atp1b2 gene and their associations with milk yield, milk composition ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-21 |
Journal Detail:
|
Title: Epilepsy research Volume: - ISSN: 1872-6844 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-6-24 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8703089 Medline TA: Epilepsy Res Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Neurology, Massachusetts General Hospital, Boston, MA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Oral cleft volumetric assessment by 3D multislice computed tomographic images.
Next Document: Efficacy of iloperidone in schizophrenia: A PANSS five-factor analysis.