Document Detail


The relationship of growth hormone to 1,25-dihydroxyvitamin D3 in intestinal calcium transport.
MedLine Citation:
PMID:  6894959     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and bovine growth hormone (bGH) on intestinal calcium transport have been assessed in vitamin D deficient rats. Calcium transport did not increase after 7 days bGH treatment. A single dose of 1,25(OH)2D3 significantly increased calcium transport in the hypophysectomized (Hx) rats treated with bGH but not in the Hx rats who did not receive bGH, unless the dosage of 2,25(OH)2D3 was increased to 500 p moles. Even though calcium transport in the Hx rats was stimulated by the high dose of 1,25(OH)2D3, this response was less in the Hx than in bGh treated group. These results suggest that growth hormone status may be important in the expression of 1,25-(OH)2D3 action on intestinal calcium transport.
Authors:
J K Yeh; J F Aloia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Metabolic bone disease & related research     Volume:  3     ISSN:  0221-8747     ISO Abbreviation:  Metab Bone Dis Relat Res     Publication Date:  1981  
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7900146     Medline TA:  Metab Bone Dis Relat Res     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  47-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcitriol
Calcium / metabolism*
Dihydroxycholecalciferols / pharmacology*
Dose-Response Relationship, Drug
Growth Hormone / pharmacology*
Hydroxycholecalciferols / pharmacology*
Hypophysectomy*
Intestinal Absorption / drug effects*
Male
Rats
Vitamin D Deficiency / metabolism
Chemical
Reg. No./Substance:
0/Dihydroxycholecalciferols; 0/Hydroxycholecalciferols; 32222-06-3/Calcitriol; 7440-70-2/Calcium; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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