Document Detail

The relationship of drinking and birth outcome in a US national sample of expectant mothers.
MedLine Citation:
PMID:  9131709     Owner:  NLM     Status:  MEDLINE    
Alcohol consumption by pregnant women and birth outcome were studied in 9953 livebirths, 3309 fetal deaths and 5332 infant deaths from the 1988 National Maternal and Infant Health Survey. In crude analyses, race, age, mother's education, prenatal care, parity, low birthweight, gestational age, smoking and alcohol consumption during pregnancy were significantly related to the occurrence of fetal deaths and infant deaths. Among women having livebirths, race, age, mother's education, prenatal care, prematurity, gestational age, smoking and alcohol consumption during pregnancy were significantly related to having a low birthweight baby (< 2500 g). In this group, women who drank more during pregnancy also smoked more, were younger and less educated than women who drank at lower levels or not at all. The relationship of alcohol consumption during pregnancy and infant birthweight for those women having livebirths was studied using multivariable linear regression. The results indicated that race, mother's education, baby's sex, parity, mother's height, mother's body mass index and smoking, but not alcohol consumption, were significantly related to birthweight. Multivariable logistic regressions were performed for the occurrence of low birthweight, fetal death and infant death. The effect of alcohol was significant in all these analyses. These results indicate that alcohol has an important relationship with birth outcome, but that for the drinking reported in this study, the alcohol effect on mean birthweight is small relative to that of other risk factors, accounting for the non-significant result in the multiple linear regression.
V B Faden; B I Graubard; M Dufour
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric and perinatal epidemiology     Volume:  11     ISSN:  0269-5022     ISO Abbreviation:  Paediatr Perinat Epidemiol     Publication Date:  1997 Apr 
Date Detail:
Created Date:  1997-07-21     Completed Date:  1997-07-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709766     Medline TA:  Paediatr Perinat Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  167-80     Citation Subset:  IM    
Division of Biometry and Epidemiology, National Institute of Alcohol Abuse and Alcoholism, Rockville, MD 20892, USA.
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MeSH Terms
Alcohol Drinking / adverse effects,  epidemiology*
Birth Weight
Chi-Square Distribution
Health Surveys
Infant Mortality
Infant, Newborn
Mothers / statistics & numerical data*
Odds Ratio
Pregnancy Outcome / epidemiology*,  ethnology
Regression Analysis
Retrospective Studies
Risk Factors
Sampling Studies
Socioeconomic Factors
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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