| The relationship between stem cell seeding efficiency and position in cell cycle. | |
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MedLine Citation:
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PMID: 427876 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The seeding efficiency of colony-forming cells from normal, regenerating and velocity-sedimented cycling and non-cycling narrow preparations was compared. Colony-forming cells in cycle were found to exhibit a 50% reduction in splenic seeding when compared to normal marrow or sedimented non-cycling cells. The results of this study indicate that the spleen colony assay underestimates the total number of colony-forming cells by a fraction which is directly related to the number of cells in cycle. |
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Authors:
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F C Monette; J B DeMello |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Cell and tissue kinetics Volume: 12 ISSN: 0008-8730 ISO Abbreviation: Cell Tissue Kinet Publication Date: 1979 Mar |
Date Detail:
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Created Date: 1979-06-11 Completed Date: 1979-06-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0174107 Medline TA: Cell Tissue Kinet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 161-75 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone Marrow / physiology Cell Cycle* Colony-Forming Units Assay* Female Hematopoietic Stem Cells / cytology* Mice Regeneration Spleen / cytology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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